Monday, 10 October 2011

Factors responsible for malignant transformation in undescended testis

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Factors responsible for malignant transformation in undescended testis

There is 40 times increased risk for malignant transformation in an undescended testis compared to testis located within the scrotum. The factors responsible for malignant transformation in undescended testis are:

Elevated temperature
Impairment of blood supply
Abnormal germ cell morphology
Endocrine dysfunction
Gonadal dysfunction

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